Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate.

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Title: Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate.
Authors: Rouleau, Francois D.1,2,3,4 (AUTHOR) Francois.rouleau.2@ulaval.ca, Dubé, Alexandre K.1,2,3,5 (AUTHOR), Gagnon-Arsenault, Isabelle1,2,3,5 (AUTHOR), Dibyachintan, Soham1,2,3,4 (AUTHOR), Pageau, Alicia1,2,3,4 (AUTHOR), Després, Philippe C.1,2,3,4 (AUTHOR), Lagüe, Patrick1,2,3,4 (AUTHOR), Landry, Christian R.1,2,3,4,5 (AUTHOR)
Source: PLoS Genetics. 4/29/2024, Vol. 20 Issue 4, p1-29. 29p.
Database: Academic Search Ultimate
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  Data: Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate.
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  Data: <searchLink fieldCode="JN" term="%22PLoS+Genetics%22">PLoS Genetics</searchLink>. 4/29/2024, Vol. 20 Issue 4, p1-29. 29p.
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        Value: 10.1371/journal.pgen.1011252
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