Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.

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Title: Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.
Authors: Yuan, Baolei1 (AUTHOR), Bi, Chongwei1 (AUTHOR), Tian, Yeteng1 (AUTHOR), Wang, Jincheng2 (AUTHOR), Jin, Yiqing1 (AUTHOR), Alsayegh, Khaled1,3 (AUTHOR), Tehseen, Muhammad1 (AUTHOR), Yi, Gang1 (AUTHOR), Zhou, Xuan1 (AUTHOR), Shao, Yanjiao4 (AUTHOR), Romero, Fernanda Vargas1 (AUTHOR), Fischle, Wolfgang1 (AUTHOR), Izpisua Belmonte, Juan Carlos1,4 (AUTHOR), Hamdan, Samir1 (AUTHOR), Huang, Yanyi2,5 (AUTHOR), Li, Mo1,6 (AUTHOR) mo.li@kaust.edu.sa
Source: BMC Biology. 4/29/2024, Vol. 22 Issue 1, p1-15. 15p.
Database: Academic Search Ultimate
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ISSN:17417007
DOI:10.1186/s12915-024-01896-z