Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of Klebsiella pneumoniae and stresses the importance to include temporal patterns for vaccine design considerations. - Heinz, Eva; Pearse, Oliver; Zuza, Allan; Bilima, Sithembile; Msefula, Chisomo; Musicha, Patrick; Siyabu, Patriciah; Tewesa, Edith; Graf, Fabrice E.; Lester, Rebecca; Lissauer, Samantha; Cornick, Jennifer; et al. (Genome Medicine, 2024)