A phase I randomized study to evaluate safety, pharmacokinetics, and pharmacodynamics of SIR2446M, a selective RIPK1 inhibitor, in healthy participants.

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Title: A phase I randomized study to evaluate safety, pharmacokinetics, and pharmacodynamics of SIR2446M, a selective RIPK1 inhibitor, in healthy participants.
Authors: Sun, Ana Liza Andresan1 (AUTHOR) asun@linear.org.au, Gillies, John David2 (AUTHOR), Shen, Yang3 (AUTHOR), Deng, Huajun3 (AUTHOR), Xue, Fenchao3 (AUTHOR), Ma, Yongfen3 (AUTHOR), Song, Linan3 (AUTHOR)
Source: CTS: Clinical & Translational Science. Jul2024, Vol. 17 Issue 7, p1-13. 13p.
Database: Academic Search Ultimate
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ISSN:17528054
DOI:10.1111/cts.13857