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Engineering a "muco‐trapping" ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19.

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Title: Engineering a "muco‐trapping" ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19.
Authors: Tiruthani, Karthik1 (AUTHOR), Cruz‐Teran, Carlos1 (AUTHOR), Chan, Jasper F. W.2,3 (AUTHOR), Ma, Alice4 (AUTHOR), McSweeney, Morgan5 (AUTHOR), Wolf, Whitney1 (AUTHOR), Yuan, Shoufeng2,3 (AUTHOR), Poon, Vincent K. M.2,3 (AUTHOR), Chan, Chris C. S.2,3 (AUTHOR), Botta, Lakshmi5 (AUTHOR), Farrer, Brian5 (AUTHOR), Stewart, Ian6 (AUTHOR), Schaefer, Alison4 (AUTHOR), Edelstein, Jasmine4 (AUTHOR), Kumar, Priya7 (AUTHOR), Arora, Harendra7 (AUTHOR), Hutchins, Jeff T.5 (AUTHOR), Hickey, Anthony J.6 (AUTHOR), Yuen, Kwok‐Yung2,3 (AUTHOR), Lai, Samuel K.1,5,8 (AUTHOR) lai@unc.edu
Source: Bioengineering & Translational Medicine. Jul2024, Vol. 9 Issue 4, p1-15. 15p.
Database: Academic Search Ultimate
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ISSN:23806761
DOI:10.1002/btm2.10650