Physiologically‐based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population.

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Title: Physiologically‐based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population.
Authors: Thompson, Elizabeth J.1,2,3 (AUTHOR), Jeong, Angela1 (AUTHOR), Helfer, Victória E.1 (AUTHOR), Shakhnovich, Valentina4,5,6 (AUTHOR), Edginton, Andrea7 (AUTHOR), Balevic, Stephen J.2,3 (AUTHOR), James, Laura P.8 (AUTHOR), Collier, David N.9 (AUTHOR), Anand, Ravinder10 (AUTHOR), Gonzalez, Daniel3,11 (AUTHOR) daniel.gonzalez@duke.edu, Benjamin, Daniel K. (AUTHOR), Kennel, Phyllis (AUTHOR), Alderman, Cheryl (AUTHOR), Sund, Zoe (AUTHOR), Opel, Kylie (AUTHOR), Beci, Rose (AUTHOR), Hornik, Chi D. (AUTHOR), Kearns, Gregory L. (AUTHOR), Paul, Ian M. (AUTHOR), Sullivan, Janice (AUTHOR)
Source: CPT: Pharmacometrics & Systems Pharmacology. Aug2024, Vol. 13 Issue 8, p1394-1408. 15p.
Database: Academic Search Ultimate
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ISSN:21638306
DOI:10.1002/psp4.13167