View in EDS HTML Full Text PDF Full Text

Computational Modeling of Drug Response Identifies Mutant-Specific Constraints for Dosing panRAF and MEK Inhibitors in Melanoma.

Saved in:
Bibliographic Details
Title: Computational Modeling of Drug Response Identifies Mutant-Specific Constraints for Dosing panRAF and MEK Inhibitors in Melanoma.
Authors: Goetz, Andrew1,2 (AUTHOR) andrew.goetz@yale.edu, Shanahan, Frances3 (AUTHOR) shanahan.frances@gene.com, Brooks, Logan4 (AUTHOR) brooksl2@gene.com, Lin, Eva5 (AUTHOR) eqlin@gene.com, Mroue, Rana3 (AUTHOR) mrouer@gene.com, Dela Cruz, Darlene6 (AUTHOR) darlened@gene.com, Hunsaker, Thomas6 (AUTHOR) hunsaket@gene.com, Czech, Bartosz7 (AUTHOR) bartosz.czech@contractors.roche.com, Dixit, Purushottam2 (AUTHOR), Segal, Udi6 (AUTHOR) segale2@gene.com, Martin, Scott5 (AUTHOR) martis85@gene.com, Foster, Scott A.3 (AUTHOR) fosters5@gene.com, Gerosa, Luca1,3 (AUTHOR) gerosa.luca@gene.com
Source: Cancers. Aug2024, Vol. 16 Issue 16, p2914. 24p.
Database: Academic Search Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: asn
DbLabel: Academic Search Ultimate
An: 179353881
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Computational Modeling of Drug Response Identifies Mutant-Specific Constraints for Dosing panRAF and MEK Inhibitors in Melanoma.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Goetz%2C+Andrew%22">Goetz, Andrew</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> andrew.goetz@yale.edu</i><br /><searchLink fieldCode="AR" term="%22Shanahan%2C+Frances%22">Shanahan, Frances</searchLink><relatesTo>3</relatesTo> (AUTHOR)<i> shanahan.frances@gene.com</i><br /><searchLink fieldCode="AR" term="%22Brooks%2C+Logan%22">Brooks, Logan</searchLink><relatesTo>4</relatesTo> (AUTHOR)<i> brooksl2@gene.com</i><br /><searchLink fieldCode="AR" term="%22Lin%2C+Eva%22">Lin, Eva</searchLink><relatesTo>5</relatesTo> (AUTHOR)<i> eqlin@gene.com</i><br /><searchLink fieldCode="AR" term="%22Mroue%2C+Rana%22">Mroue, Rana</searchLink><relatesTo>3</relatesTo> (AUTHOR)<i> mrouer@gene.com</i><br /><searchLink fieldCode="AR" term="%22Dela+Cruz%2C+Darlene%22">Dela Cruz, Darlene</searchLink><relatesTo>6</relatesTo> (AUTHOR)<i> darlened@gene.com</i><br /><searchLink fieldCode="AR" term="%22Hunsaker%2C+Thomas%22">Hunsaker, Thomas</searchLink><relatesTo>6</relatesTo> (AUTHOR)<i> hunsaket@gene.com</i><br /><searchLink fieldCode="AR" term="%22Czech%2C+Bartosz%22">Czech, Bartosz</searchLink><relatesTo>7</relatesTo> (AUTHOR)<i> bartosz.czech@contractors.roche.com</i><br /><searchLink fieldCode="AR" term="%22Dixit%2C+Purushottam%22">Dixit, Purushottam</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Segal%2C+Udi%22">Segal, Udi</searchLink><relatesTo>6</relatesTo> (AUTHOR)<i> segale2@gene.com</i><br /><searchLink fieldCode="AR" term="%22Martin%2C+Scott%22">Martin, Scott</searchLink><relatesTo>5</relatesTo> (AUTHOR)<i> martis85@gene.com</i><br /><searchLink fieldCode="AR" term="%22Foster%2C+Scott+A%2E%22">Foster, Scott A.</searchLink><relatesTo>3</relatesTo> (AUTHOR)<i> fosters5@gene.com</i><br /><searchLink fieldCode="AR" term="%22Gerosa%2C+Luca%22">Gerosa, Luca</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<i> gerosa.luca@gene.com</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Cancers%22">Cancers</searchLink>. Aug2024, Vol. 16 Issue 16, p2914. 24p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=179353881
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3390/cancers16162914
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 24
        StartPage: 2914
    Titles:
      – TitleFull: Computational Modeling of Drug Response Identifies Mutant-Specific Constraints for Dosing panRAF and MEK Inhibitors in Melanoma.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Goetz, Andrew
      – PersonEntity:
          Name:
            NameFull: Shanahan, Frances
      – PersonEntity:
          Name:
            NameFull: Brooks, Logan
      – PersonEntity:
          Name:
            NameFull: Lin, Eva
      – PersonEntity:
          Name:
            NameFull: Mroue, Rana
      – PersonEntity:
          Name:
            NameFull: Dela Cruz, Darlene
      – PersonEntity:
          Name:
            NameFull: Hunsaker, Thomas
      – PersonEntity:
          Name:
            NameFull: Czech, Bartosz
      – PersonEntity:
          Name:
            NameFull: Dixit, Purushottam
      – PersonEntity:
          Name:
            NameFull: Segal, Udi
      – PersonEntity:
          Name:
            NameFull: Martin, Scott
      – PersonEntity:
          Name:
            NameFull: Foster, Scott A.
      – PersonEntity:
          Name:
            NameFull: Gerosa, Luca
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 08
              Text: Aug2024
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-print
              Value: 20726694
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 16
          Titles:
            – TitleFull: Cancers
              Type: main
ResultId 1