Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Muscarinic M3 Receptor‐Positive Allosteric Modulator ASP8302 Following Single and Multiple Ascending Oral Doses in Healthy Volunteers.
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| Title: | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Muscarinic M |
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| Authors: | Takusagawa, Shin1 (AUTHOR) shin.takusagawa@astellas.com, Treijtel, Nicoline2 (AUTHOR), Saito, Masako1 (AUTHOR), Michon, Ingrid2 (AUTHOR), Miyatake, Daisuke1 (AUTHOR), Osaki, Fumio1 (AUTHOR), Guro, Sayuri1 (AUTHOR), Fadini, Tomasso3 (AUTHOR), Sekino, Hisakuni4 (AUTHOR), Aarden‐Bakker, Marlous2 (AUTHOR), Kuroishi, Kentaro1 (AUTHOR), van Till, Jan Willem Olivier5 (AUTHOR), Groenendaal‐van de Meent, Dorien2 (AUTHOR), de Vries, Michiel2 (AUTHOR) |
| Source: | Clinical Pharmacology in Drug Development. Oct2024, Vol. 13 Issue 10, p1130-1142. 13p. |
| Database: | Academic Search Ultimate |
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| Header | DbId: asn DbLabel: Academic Search Ultimate An: 180088961 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Muscarinic M<subscript>3</subscript> Receptor‐Positive Allosteric Modulator ASP8302 Following Single and Multiple Ascending Oral Doses in Healthy Volunteers. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Takusagawa%2C+Shin%22">Takusagawa, Shin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> shin.takusagawa@astellas.com</i><br /><searchLink fieldCode="AR" term="%22Treijtel%2C+Nicoline%22">Treijtel, Nicoline</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Saito%2C+Masako%22">Saito, Masako</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Michon%2C+Ingrid%22">Michon, Ingrid</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miyatake%2C+Daisuke%22">Miyatake, Daisuke</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Osaki%2C+Fumio%22">Osaki, Fumio</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Guro%2C+Sayuri%22">Guro, Sayuri</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fadini%2C+Tomasso%22">Fadini, Tomasso</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sekino%2C+Hisakuni%22">Sekino, Hisakuni</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Aarden‐Bakker%2C+Marlous%22">Aarden‐Bakker, Marlous</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kuroishi%2C+Kentaro%22">Kuroishi, Kentaro</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22van+Till%2C+Jan+Willem+Olivier%22">van Till, Jan Willem Olivier</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Groenendaal‐van+de+Meent%2C+Dorien%22">Groenendaal‐van de Meent, Dorien</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22de+Vries%2C+Michiel%22">de Vries, Michiel</searchLink><relatesTo>2</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Clinical+Pharmacology+in+Drug+Development%22">Clinical Pharmacology in Drug Development</searchLink>. Oct2024, Vol. 13 Issue 10, p1130-1142. 13p. |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=180088961 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/cpdd.1460 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 1130 Titles: – TitleFull: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Muscarinic M3 Receptor‐Positive Allosteric Modulator ASP8302 Following Single and Multiple Ascending Oral Doses in Healthy Volunteers. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Takusagawa, Shin – PersonEntity: Name: NameFull: Treijtel, Nicoline – PersonEntity: Name: NameFull: Saito, Masako – PersonEntity: Name: NameFull: Michon, Ingrid – PersonEntity: Name: NameFull: Miyatake, Daisuke – PersonEntity: Name: NameFull: Osaki, Fumio – PersonEntity: Name: NameFull: Guro, Sayuri – PersonEntity: Name: NameFull: Fadini, Tomasso – PersonEntity: Name: NameFull: Sekino, Hisakuni – PersonEntity: Name: NameFull: Aarden‐Bakker, Marlous – PersonEntity: Name: NameFull: Kuroishi, Kentaro – PersonEntity: Name: NameFull: van Till, Jan Willem Olivier – PersonEntity: Name: NameFull: Groenendaal‐van de Meent, Dorien – PersonEntity: Name: NameFull: de Vries, Michiel IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 2160763X Numbering: – Type: volume Value: 13 – Type: issue Value: 10 Titles: – TitleFull: Clinical Pharmacology in Drug Development Type: main |
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