The N-terminal activation function AF-1 domain of ERα interacts directly with the C-terminal AF-2-holding ligand-binding domain to recruit the coactivator proteins. - Liu, Xiaohui; Matsuyama, Yutaka; Sugiyama, Makiko; Suyama, Keitaro; Nose, Takeru; Shimohigashi, Miki; Shimohigashi, Yasuyuki (PLoS ONE, 2024)