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Notch1 blockade by a novel, selective anti-Notch1 neutralizing antibody improves immunotherapy efficacy in melanoma by promoting an inflamed TME.

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Title: Notch1 blockade by a novel, selective anti-Notch1 neutralizing antibody improves immunotherapy efficacy in melanoma by promoting an inflamed TME.
Authors: de Freitas, Juliano Tiburcio1 (AUTHOR), Thakur, Varsha1 (AUTHOR), LaPorte, Kathryn M.2 (AUTHOR), Thakur, Vijay S.3 (AUTHOR), Flores, Brian1 (AUTHOR), Caicedo, Valentina1 (AUTHOR), Ajaegbu, Chioma G. E.1 (AUTHOR), Ingrasci, Giuseppe1 (AUTHOR), Lipman, Zoe M.1 (AUTHOR), Zhang, Keman4 (AUTHOR), Qiu, Hong4 (AUTHOR), Malek, Thomas R.2 (AUTHOR), Bedogni, Barbara1 (AUTHOR) bxb602@miami.edu
Source: Journal of Experimental & Clinical Cancer Research (17569966). 11/4/2024, Vol. 43 Issue 1, p1-14. 14p.
Database: Academic Search Ultimate
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ISSN:17569966
DOI:10.1186/s13046-024-03214-5