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A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.

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Title: A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.
Authors: Xie, Stanley C.1,2 (AUTHOR), Tai, Chia-Wei1 (AUTHOR), Morton, Craig J.3 (AUTHOR), Ma, Liting4 (AUTHOR), Huang, Shih-Chung4 (AUTHOR), Wittlin, Sergio5,6 (AUTHOR), Du, Yawei1 (AUTHOR), Hu, Yongbo4 (AUTHOR), Dogovski, Con1 (AUTHOR), Salimimarand, Mina7 (AUTHOR), Griffin, Robert4 (AUTHOR), England, Dylan4 (AUTHOR), de la Cruz, Elisa4 (AUTHOR), Deni, Ioanna8,9 (AUTHOR), Yeo, Tomas8,9 (AUTHOR), Burkhard, Anna Y.8,9 (AUTHOR), Striepen, Josefine8,9 (AUTHOR), Schindler, Kyra A.8,9 (AUTHOR), Crespo, Benigno10 (AUTHOR), Gamo, Francisco J.10 (AUTHOR)
Source: PLoS Pathogens. 12/9/2024, Vol. 20 Issue 12, p1-28. 28p.
Database: Academic Search Ultimate
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ISSN:15537366
DOI:10.1371/journal.ppat.1012429