Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer's disease ligands.

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Title: Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer's disease ligands.
Authors: Greven, Jessica A.1 (AUTHOR), Wydra, Joshua R.1 (AUTHOR), Greer, Rory A.2 (AUTHOR), Zhi, Cynthia1 (AUTHOR), Price, David A.3 (AUTHOR), Svoboda, Jordyn D.1 (AUTHOR), Camitta, Christopher L. M.1 (AUTHOR), Washington, Mya1 (AUTHOR), Leung, Daisy W.3 (AUTHOR), Song, Yuhua2 (AUTHOR), Alexander-Brett, Jen1,4,5,6 (AUTHOR) jalexand@wustl.edu, Brett, Tom J.1,4,6,7,8,9 (AUTHOR) tbrett@wustl.edu
Source: Molecular Neurodegeneration. 1/9/2025, Vol. 20 Issue 1, p1-20. 20p.
Database: Academic Search Ultimate
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ISSN:17501326
DOI:10.1186/s13024-024-00795-9