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Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4′-Fluorouridine.

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Title: Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4′-Fluorouridine.
Authors: Yin, Peiqi1 (AUTHOR), Sobolik, Elizabeth B.2 (AUTHOR), May, Nicholas A.3 (AUTHOR), Wang, Sainan4 (AUTHOR), Fayed, Atef1 (AUTHOR), Vyshenska, Dariia2 (AUTHOR), Drobish, Adam M.3 (AUTHOR), Parks, M. Guston3 (AUTHOR), Lello, Laura Sandra4 (AUTHOR), Merits, Andres4 (AUTHOR), Morrison, Thomas E.3 (AUTHOR), Greninger, Alexander L.2 (AUTHOR), Kielian, Margaret1 (AUTHOR) margaret.kielian@einsteinmed.edu
Source: PLoS Pathogens. 1/13/2025, Vol. 21 Issue 1, p1-24. 24p.
Database: Academic Search Ultimate
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ISSN:15537366
DOI:10.1371/journal.ppat.1012859