Assessing Drug–Drug Interaction and Food Effect for BCS Class 2 Compound BI 730357 (Retinoic Acid-Related Orphan Receptor Gamma Antagonist, Bevurogant) Using a Physiology-Based Pharmacokinetics Modeling (PBPK) Approach with Semi-Mechanistic Absorption
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| Title: | Assessing Drug–Drug Interaction and Food Effect for BCS Class 2 Compound BI 730357 (Retinoic Acid-Related Orphan Receptor Gamma Antagonist, Bevurogant) Using a Physiology-Based Pharmacokinetics Modeling (PBPK) Approach with Semi-Mechanistic Absorption |
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| Authors: | Kanacher, Tobias1 (AUTHOR) tobias.kanacher@pharmetheus.com, Sjögren, Erik1,2 (AUTHOR), Korell, Julia2,3 (AUTHOR), Plan, Elodie L.1 (AUTHOR), Gómez-Mantilla, Jose David2,3 (AUTHOR), Ince, Ibrahim3 (AUTHOR) |
| Source: | Pharmaceutics. Mar2025, Vol. 17 Issue 3, p314. 16p. |
| Database: | Academic Search Ultimate |
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