Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study.

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Title: Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study.
Authors: Jia, Yuchao1,2, Zhao, Haifan1,2, Huang, Shengbo1,2, Xu, Baoshan1 baoshanxu99@tmu.edu.cn
Source: Journal of Orthopaedic Surgery & Research. 5/3/2025, Vol. 20 Issue 1, p1-11. 11p.
Database: Academic Search Ultimate
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  Data: Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study.
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  Data: <searchLink fieldCode="AR" term="%22Jia%2C+Yuchao%22">Jia, Yuchao</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhao%2C+Haifan%22">Zhao, Haifan</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Huang%2C+Shengbo%22">Huang, Shengbo</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Xu%2C+Baoshan%22">Xu, Baoshan</searchLink><relatesTo>1</relatesTo><i> baoshanxu99@tmu.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Orthopaedic+Surgery+%26+Research%22">Journal of Orthopaedic Surgery & Research</searchLink>. 5/3/2025, Vol. 20 Issue 1, p1-11. 11p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=184913750
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1186/s13018-025-05863-4
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      – Code: eng
        Text: English
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      – TitleFull: Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study.
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            NameFull: Jia, Yuchao
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            NameFull: Zhao, Haifan
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            NameFull: Huang, Shengbo
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              Text: 5/3/2025
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              Y: 2025
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