Combination therapy of adagrasib and abemaciclib in non-small cell lung cancer brain metastasis models genomically characterized by KRAS-G12C and homozygous loss of CDKN2A.

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Title: Combination therapy of adagrasib and abemaciclib in non-small cell lung cancer brain metastasis models genomically characterized by KRAS-G12C and homozygous loss of CDKN2A.
Authors: Migliarese, Christian1 (AUTHOR), Sadeh, Yinon1 (AUTHOR), Torrini, Consuelo2 (AUTHOR), Turna Demir, Fatma1,3 (AUTHOR), Nayyar, Naema2 (AUTHOR), Yamazawa, Erika2 (AUTHOR), Ishikawa, Yuu1 (AUTHOR), Ijad, Nazanin2 (AUTHOR), Summers, Elizabeth J.2 (AUTHOR), Elliott, Adam4 (AUTHOR), Rahbaek, Lisa4 (AUTHOR), Saechao, Barbara4 (AUTHOR), Hallin, Jill4 (AUTHOR), Brastianos, Priscilla K.2 (AUTHOR) pbrastianos@mgh.harvard.edu, Wakimoto, Hiroaki1 (AUTHOR) hwakimoto@mgh.harvard.edu
Source: Acta Neuropathologica Communications. 5/2/2025, Vol. 13 Issue 1, p1-14. 14p.
Database: Academic Search Ultimate
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ISSN:20515960
DOI:10.1186/s40478-025-01993-2