ILOBONE: A phase I/IIa randomized controlled trial to assess the safety and feasibility of local iloprost therapy for enhancing proximal humerus fracture healing– a pilot study design.

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Title: ILOBONE: A phase I/IIa randomized controlled trial to assess the safety and feasibility of local iloprost therapy for enhancing proximal humerus fracture healing– a pilot study design.
Authors: Elazaly, Hisham1,2,3, Dimitriou, Ioanna Maria2,3,4, Maleitzke, Tazio1,2,5,6,7, Dahne, Michael1, Jaecker, Vera1, Maerdian, Sven1, Tafelski, Sascha1, Diekhoff, Torsten8, Lindner, Tobias9, Akgün, Doruk1, Mielke, Anna-Maria1, Paksoy, Alp1, Amini, Dominik Adl1, Planatscher, Elisa Marie1, Leopold, Vincent1, González-Khatib, Susana1, Köhli, Paul Christoph1,2,10, Niemann, Marcel1,2,4, Hildebrandt, Alexander1, Oehme, Stephan1
Source: Journal of Orthopaedic Surgery & Research. 5/22/2025, Vol. 20 Issue 1, p1-10. 10p.
Database: Academic Search Ultimate
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ISSN:1749799X
DOI:10.1186/s13018-025-05865-2