The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of changes in β-catenin abundance.

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Title: The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of changes in β-catenin abundance.
Authors: McKenna, Joseph K.1 (AUTHOR), Wu, Yalan1 (AUTHOR), Sonkusre, Praveen1 (AUTHOR), Sinclear, Caleb K.1 (AUTHOR), Chari, Raj2 (AUTHOR), Lebensohn, Andres M.1 (AUTHOR) andres.lebensohn@nih.gov
Source: PLoS Genetics. 5/27/2025, Vol. 21 Issue 5, p1-35. 35p.
Database: Academic Search Ultimate
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