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Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.

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Title: Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.
Authors: Wei, Spencer C.1 (AUTHOR) spencer.wei@gmail.com, Cantor, Aaron J.1 (AUTHOR), Walleshauser, Jack1 (AUTHOR), Mepani, Rina1 (AUTHOR), Melton, Kory1 (AUTHOR), Bans, Ashil1 (AUTHOR), Khekare, Prachi1 (AUTHOR), Gupta, Suhani1 (AUTHOR), Wang, Jonathan1 (AUTHOR), Soares, Craig1 (AUTHOR), Kiwan, Radwan1 (AUTHOR), Lee, Jieun1 (AUTHOR), McCawley, Shannon1 (AUTHOR), Jani, Vihasi1 (AUTHOR), Leong, Weng In1 (AUTHOR), Shahi, Pawan K.2,3 (AUTHOR), Chan, Jean1 (AUTHOR), Boivin, Pierre1 (AUTHOR), Otoupal, Peter1 (AUTHOR), Pattnaik, Bikash R.2,3,4 (AUTHOR)
Source: PLoS ONE. 6/24/2025, Vol. 20 Issue 6, p1-24. 24p.
Database: Academic Search Ultimate
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