Elucidating the role of N-myristoylation in the excessive membrane localization of PD-L1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy.
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| Title: | Elucidating the role of N-myristoylation in the excessive membrane localization of PD-L1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy. |
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| Authors: | Zhao, Haoming1,2 (AUTHOR), Zhang, Zhen1,2,3 (AUTHOR), Zhang, Chaojun1,2 (AUTHOR), Ma, Hexin1,2 (AUTHOR), Wan, Qingqing1,2 (AUTHOR), Zhao, Xinran1,2 (AUTHOR), Wang, Xu1,2 (AUTHOR), Yan, Ming1,2 (AUTHOR), Guo, Haiyan4 (AUTHOR), Zhang, Jianjun1,2 (AUTHOR) zjjbio@sjtu.edu.cn, Chen, Wantao1,2,3 (AUTHOR) chenwantao196323@sjtu.edu.cn |
| Source: | Journal of Experimental & Clinical Cancer Research (17569966). 7/2/2025, Vol. 44 Issue 1, p1-22. 22p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 17569966 |
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| DOI: | 10.1186/s13046-025-03438-z |