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SETDB1 knockdown boosts recombinant protein in CHO cells via epigenetic transcriptional silencing.

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Title: SETDB1 knockdown boosts recombinant protein in CHO cells via epigenetic transcriptional silencing.
Authors: Lu, Jiang-Tao1,2,3 (AUTHOR), Zhang, Miao1,2,3 (AUTHOR), Gao, Yan-Ping1,2,3 (AUTHOR), Yang, Lu-Lu1,2,3 (AUTHOR), Cui, Zhao-Ming1,2,3 (AUTHOR), Han, Ming-Ming1,2,3 (AUTHOR), Zhang, Xi1,2,3 (AUTHOR), Xu, Hong-Yan1 (AUTHOR), Wang, Xiao-Yin2,3,4 (AUTHOR), Qiu, Le-Le4 (AUTHOR), Hua, Zi-Chun5,6 (AUTHOR), Wang, Tian-Yun2,3,4 (AUTHOR) wtianyuncn@126.com, Jia, Yan-Long1,2,3,5 (AUTHOR) yanlongjia@126.com
Source: AMB Express. 7/26/2025, Vol. 15 Issue 1, p1-13. 13p.
Database: Academic Search Ultimate
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ISSN:21910855
DOI:10.1186/s13568-025-01914-5