View in EDS HTML Full Text PDF Full Text

First‐in‐Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral Complement Factor D Inhibitor BCX9930 in Healthy Participants.

Saved in:
Bibliographic Details
Title: First‐in‐Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral Complement Factor D Inhibitor BCX9930 in Healthy Participants.
Authors: Davidson, Matthew1 mdavidson@biocryst.com, Chen, Xilin2, Mathis, Amanda1, Dobo, Sylvia1, Cornpropst, Melanie1, Zhu, Fugang2, Parker, Cynthia2, Reynolds, David1, Babu, Yarlagadda S.2, Mair, Stuart3, Sheridan, William P.1
Source: Journal of Clinical Pharmacology. Sep2025, Vol. 65 Issue 9, p1116-1126. 11p.
Database: Academic Search Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: asn
DbLabel: Academic Search Ultimate
An: 187636572
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: First‐in‐Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral Complement Factor D Inhibitor BCX9930 in Healthy Participants.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Davidson%2C+Matthew%22">Davidson, Matthew</searchLink><relatesTo>1</relatesTo><i> mdavidson@biocryst.com</i><br /><searchLink fieldCode="AR" term="%22Chen%2C+Xilin%22">Chen, Xilin</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Mathis%2C+Amanda%22">Mathis, Amanda</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Dobo%2C+Sylvia%22">Dobo, Sylvia</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Cornpropst%2C+Melanie%22">Cornpropst, Melanie</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhu%2C+Fugang%22">Zhu, Fugang</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Parker%2C+Cynthia%22">Parker, Cynthia</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Reynolds%2C+David%22">Reynolds, David</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Babu%2C+Yarlagadda+S%2E%22">Babu, Yarlagadda S.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Mair%2C+Stuart%22">Mair, Stuart</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Sheridan%2C+William+P%2E%22">Sheridan, William P.</searchLink><relatesTo>1</relatesTo>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Journal+of+Clinical+Pharmacology%22">Journal of Clinical Pharmacology</searchLink>. Sep2025, Vol. 65 Issue 9, p1116-1126. 11p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=187636572
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/jcph.70032
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 1116
    Titles:
      – TitleFull: First‐in‐Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral Complement Factor D Inhibitor BCX9930 in Healthy Participants.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Davidson, Matthew
      – PersonEntity:
          Name:
            NameFull: Chen, Xilin
      – PersonEntity:
          Name:
            NameFull: Mathis, Amanda
      – PersonEntity:
          Name:
            NameFull: Dobo, Sylvia
      – PersonEntity:
          Name:
            NameFull: Cornpropst, Melanie
      – PersonEntity:
          Name:
            NameFull: Zhu, Fugang
      – PersonEntity:
          Name:
            NameFull: Parker, Cynthia
      – PersonEntity:
          Name:
            NameFull: Reynolds, David
      – PersonEntity:
          Name:
            NameFull: Babu, Yarlagadda S.
      – PersonEntity:
          Name:
            NameFull: Mair, Stuart
      – PersonEntity:
          Name:
            NameFull: Sheridan, William P.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: Sep2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 00912700
          Numbering:
            – Type: volume
              Value: 65
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Journal of Clinical Pharmacology
              Type: main
ResultId 1