Adenine base editing rescues disrupted BCKDH function and reduces BCAAs toxic accumulation in maple syrup urine disease patient iPSC-hepatic organoids.
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| Title: | Adenine base editing rescues disrupted BCKDH function and reduces BCAAs toxic accumulation in maple syrup urine disease patient iPSC-hepatic organoids. |
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| Authors: | Zhang, Haiyan1,2 (AUTHOR), Wan, Zirui3,4,5 (AUTHOR), Li, Xiaomei2,6 (AUTHOR), Wang, Bin1,2 (AUTHOR), Guan, Jingyun1,2 (AUTHOR), Li, Yue1,2 (AUTHOR), Jin, Xiaohua3,5 (AUTHOR) jinxiaohua@nrifp.org.cn, Ma, Xu3,4,5 (AUTHOR) maxu_fg@nrifp.org.cn, Liu, Guohua1,2 (AUTHOR) liuguohua0204@163.com |
| Source: | Stem Cell Research & Therapy. 9/26/2025, Vol. 16 Issue 1, p1-17. 17p. |
| Database: | Academic Search Ultimate |
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| Header | DbId: asn DbLabel: Academic Search Ultimate An: 188318811 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Adenine base editing rescues disrupted BCKDH function and reduces BCAAs toxic accumulation in maple syrup urine disease patient iPSC-hepatic organoids. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Zhang%2C+Haiyan%22">Zhang, Haiyan</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wan%2C+Zirui%22">Wan, Zirui</searchLink><relatesTo>3,4,5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Xiaomei%22">Li, Xiaomei</searchLink><relatesTo>2,6</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Bin%22">Wang, Bin</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Guan%2C+Jingyun%22">Guan, Jingyun</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Yue%22">Li, Yue</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jin%2C+Xiaohua%22">Jin, Xiaohua</searchLink><relatesTo>3,5</relatesTo> (AUTHOR)<i> jinxiaohua@nrifp.org.cn</i><br /><searchLink fieldCode="AR" term="%22Ma%2C+Xu%22">Ma, Xu</searchLink><relatesTo>3,4,5</relatesTo> (AUTHOR)<i> maxu_fg@nrifp.org.cn</i><br /><searchLink fieldCode="AR" term="%22Liu%2C+Guohua%22">Liu, Guohua</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> liuguohua0204@163.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Stem+Cell+Research+%26+Therapy%22">Stem Cell Research & Therapy</searchLink>. 9/26/2025, Vol. 16 Issue 1, p1-17. 17p. |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=188318811 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13287-025-04630-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 17 StartPage: 1 Titles: – TitleFull: Adenine base editing rescues disrupted BCKDH function and reduces BCAAs toxic accumulation in maple syrup urine disease patient iPSC-hepatic organoids. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhang, Haiyan – PersonEntity: Name: NameFull: Wan, Zirui – PersonEntity: Name: NameFull: Li, Xiaomei – PersonEntity: Name: NameFull: Wang, Bin – PersonEntity: Name: NameFull: Guan, Jingyun – PersonEntity: Name: NameFull: Li, Yue – PersonEntity: Name: NameFull: Jin, Xiaohua – PersonEntity: Name: NameFull: Ma, Xu – PersonEntity: Name: NameFull: Liu, Guohua IsPartOfRelationships: – BibEntity: Dates: – D: 26 M: 09 Text: 9/26/2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 17576512 Numbering: – Type: volume Value: 16 – Type: issue Value: 1 Titles: – TitleFull: Stem Cell Research & Therapy Type: main |
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