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A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma.

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Title: A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma.
Authors: Singh, Kirit1,2 (AUTHOR), Foster, Matthew W.3 (AUTHOR), Violette, Marlene J.3 (AUTHOR), Corcoran, Anna M.1,2 (AUTHOR), Hotchkiss, Kelly M.1,2 (AUTHOR), Railton, Chelsea O.1,2 (AUTHOR), Blandford, Emily E.1,2 (AUTHOR), Blethen, Kathryn E.1,2 (AUTHOR), Thomas, Elizabeth L.1,4 (AUTHOR), McIntosh, William C.1,2 (AUTHOR), Ashley, David M.1 (AUTHOR), Desjardins, Annick1 (AUTHOR), Friedman, Henry S.1 (AUTHOR), Johnson, Margaret O.1 (AUTHOR), Friedman, Allan1,2 (AUTHOR), Keir, Stephen1 (AUTHOR), Buckley, Evan D.5 (AUTHOR), Herndon, James E.5,6 (AUTHOR), McLendon, Roger E.1,2,4 (AUTHOR), Sampson, John H.7 (AUTHOR)
Source: Scientific Reports. 10/23/2025, Vol. 15 Issue 1, p1-14. 14p.
Database: Academic Search Ultimate
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              Text: 10/23/2025
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