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Pharmacological inhibition of SPAK-NKCC1 complex attenuates astrogliosis and restores cerebral blood flow in a mouse model of VCID.

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Title: Pharmacological inhibition of SPAK-NKCC1 complex attenuates astrogliosis and restores cerebral blood flow in a mouse model of VCID.
Authors: Habib, Khadija1,2 (AUTHOR) khhabib.31@gmail.com, Sultan, Md. Tipu1,2 (AUTHOR) tipubge@yahoo.com, Jahan, Israt1,2 (AUTHOR) ijaimy@gmail.com, Rahman, Md. Shamim1,3 (AUTHOR) shamim.bge.ku12@gmail.com, Kundu, Sujan Kumar1,3 (AUTHOR) sujanku13@gmail.com, Sarker, Barnali1,3 (AUTHOR) barnalisarker16@gmail.com, Islam, Rabia4 (AUTHOR) sharmeenmn@gmail.com, Ahmed, Tanvir1 (AUTHOR) tanvir203ahmed@gmail.com, Mendez, Ian A.2 (AUTHOR) iamendez2@utep.edu, Cao, Guodong5,6 (AUTHOR) caoxgx@upmc.edu, Sun, Dandan5,6 (AUTHOR) sund@upmc.edu, Tesic, Vesna1,7 (AUTHOR) vesna.tesic@lsuhs.edu, Bhuiyan, Mohammad Iqbal H.1,2,3,7 (AUTHOR) mohammad.iqbal@lsuhs.edu
Source: Acta Neuropathologica Communications. 10/24/2025, Vol. 13 Issue 1, p1-21. 21p.
Database: Academic Search Ultimate
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  Data: Pharmacological inhibition of SPAK-NKCC1 complex attenuates astrogliosis and restores cerebral blood flow in a mouse model of VCID.
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  Data: <searchLink fieldCode="AR" term="%22Habib%2C+Khadija%22">Habib, Khadija</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> khhabib.31@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Sultan%2C+Md%2E+Tipu%22">Sultan, Md. Tipu</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> tipubge@yahoo.com</i><br /><searchLink fieldCode="AR" term="%22Jahan%2C+Israt%22">Jahan, Israt</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> ijaimy@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Rahman%2C+Md%2E+Shamim%22">Rahman, Md. Shamim</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<i> shamim.bge.ku12@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Kundu%2C+Sujan+Kumar%22">Kundu, Sujan Kumar</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<i> sujanku13@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Sarker%2C+Barnali%22">Sarker, Barnali</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<i> barnalisarker16@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Islam%2C+Rabia%22">Islam, Rabia</searchLink><relatesTo>4</relatesTo> (AUTHOR)<i> sharmeenmn@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Ahmed%2C+Tanvir%22">Ahmed, Tanvir</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> tanvir203ahmed@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Mendez%2C+Ian+A%2E%22">Mendez, Ian A.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> iamendez2@utep.edu</i><br /><searchLink fieldCode="AR" term="%22Cao%2C+Guodong%22">Cao, Guodong</searchLink><relatesTo>5,6</relatesTo> (AUTHOR)<i> caoxgx@upmc.edu</i><br /><searchLink fieldCode="AR" term="%22Sun%2C+Dandan%22">Sun, Dandan</searchLink><relatesTo>5,6</relatesTo> (AUTHOR)<i> sund@upmc.edu</i><br /><searchLink fieldCode="AR" term="%22Tesic%2C+Vesna%22">Tesic, Vesna</searchLink><relatesTo>1,7</relatesTo> (AUTHOR)<i> vesna.tesic@lsuhs.edu</i><br /><searchLink fieldCode="AR" term="%22Bhuiyan%2C+Mohammad+Iqbal+H%2E%22">Bhuiyan, Mohammad Iqbal H.</searchLink><relatesTo>1,2,3,7</relatesTo> (AUTHOR)<i> mohammad.iqbal@lsuhs.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22Acta+Neuropathologica+Communications%22">Acta Neuropathologica Communications</searchLink>. 10/24/2025, Vol. 13 Issue 1, p1-21. 21p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=188901020
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        Value: 10.1186/s40478-025-02137-2
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              Text: 10/24/2025
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              Y: 2025
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