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Targeting CXCR2 in prostate cancer cells can block CD47-SIRPα interaction and reverse M2 macrophage polarization in the TME.

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Title: Targeting CXCR2 in prostate cancer cells can block CD47-SIRPα interaction and reverse M2 macrophage polarization in the TME.
Authors: Sun, Yi1 (AUTHOR) yisun666@gzhmu.edu.cn, Ren, Shangqing2 (AUTHOR) Rsq0516@163.com, Wen, Wei3 (AUTHOR) kingfrankman@foxmail.com, Jing, Jun4 (AUTHOR) jingj6@mail.sysu.edu.cn, Luo, Xu5 (AUTHOR) lxibcde@163.com, Shao, Shuai6 (AUTHOR) shaooshuai@163.com, Duan, Ruiqi7 (AUTHOR) duanxiaoyi2016@163.com, Zeng, Guohua1 (AUTHOR) gzgyzgh@vip.sina.com, Guo, Ju8 (AUTHOR) ndyfy02371@ncu.edu.cn
Source: Molecular Cancer. 10/30/2025, Vol. 24 Issue 1, p1-26. 26p.
Database: Academic Search Ultimate
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ISSN:14764598
DOI:10.1186/s12943-025-02436-1