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First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies.

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Title: First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies.
Authors: Mahadevan, Daruka1 (AUTHOR) mahadevand@uthscsa.edu, Barve, Minal2 (AUTHOR), Mahalingam, Devalingam3 (AUTHOR), Parekh, Jay1 (AUTHOR), Kurman, Michael4 (AUTHOR), Strauss, James4 (AUTHOR), Tremaine, Larry4 (AUTHOR), Hromas, Robert1,4 (AUTHOR), Sills, Joshua4 (AUTHOR), McCulloch, John4 (AUTHOR), Harkey, John4 (AUTHOR), Suberg, Stacy4 (AUTHOR), Zimmerman, Lisa4 (AUTHOR), Zheng, Guangrong5 (AUTHOR), Zhou, Daohong1 (AUTHOR)
Source: Journal of Hematology & Oncology. 11/12/2025, Vol. 18 Issue 1, p1-12. 12p.
Database: Academic Search Ultimate
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  Data: First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies.
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Hematology+%26+Oncology%22">Journal of Hematology & Oncology</searchLink>. 11/12/2025, Vol. 18 Issue 1, p1-12. 12p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=189253387
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        Value: 10.1186/s13045-025-01753-8
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      – Code: eng
        Text: English
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        PageCount: 12
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      – TitleFull: First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies.
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              Text: 11/12/2025
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              Y: 2025
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