First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies.

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Bibliographic Details
Title: First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies.
Authors: Mahadevan, Daruka1 (AUTHOR) mahadevand@uthscsa.edu, Barve, Minal2 (AUTHOR), Mahalingam, Devalingam3 (AUTHOR), Parekh, Jay1 (AUTHOR), Kurman, Michael4 (AUTHOR), Strauss, James4 (AUTHOR), Tremaine, Larry4 (AUTHOR), Hromas, Robert1,4 (AUTHOR), Sills, Joshua4 (AUTHOR), McCulloch, John4 (AUTHOR), Harkey, John4 (AUTHOR), Suberg, Stacy4 (AUTHOR), Zimmerman, Lisa4 (AUTHOR), Zheng, Guangrong5 (AUTHOR), Zhou, Daohong1 (AUTHOR)
Source: Journal of Hematology & Oncology. 11/12/2025, Vol. 18 Issue 1, p1-12. 12p.
Database: Academic Search Ultimate
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