A framework to determine active neurons and networks within the mouse brain reveals how brain activity changes over the course of the day. - Sun, Guanhua; Mano, Tomoyuki; Shi, Shoi; Li, Alvin; Ode, Koji L; Rosi-Andersen, Alex; Pedron, Erica; Brown, Steven A.; Ueda, Hiroki R; Kompotis, Konstantinos; Forger, Daniel B. (PLoS Biology, 2025)