The B169L protein of African swine fever virus functions as a viroporin that activates the calcium-mediated inflammasome. - Li, Jiaqi; Li, Qiguang; Wang, Yanjin; Guo, Zhanhao; Qu, Yuxin; Wang, Xiao; Deng, Hao; Dai, Jingwen; Li, Lian-Feng; He, Wen-Rui; Ren, Haojie; Gao, Zhaobing; et al. (PLoS Pathogens, 2025)