1000TiP Novel next generation PARP1-selective and CNS penetrant inhibitor DSB2455: A phase Ia/Ib open label, multi-centre dose escalation study with expansion cohorts to assess the safety, tolerability, and activity as monotherapy in participants with advanced malignancies
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| Title: | 1000TiP Novel next generation PARP1-selective and CNS penetrant inhibitor DSB2455: A phase Ia/Ib open label, multi-centre dose escalation study with expansion cohorts to assess the safety, tolerability, and activity as monotherapy in participants with advanced malignancies |
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| Authors: | Yarza, R.1 (AUTHOR), Garralda, E.2 (AUTHOR), Sánchez Perez, V.3 (AUTHOR), De Velasco Oria, G.A.4 (AUTHOR), Lorusso, P.M.5 (AUTHOR), Rodríguez, R.M.6 (AUTHOR), Kristeleit, R.S.7 (AUTHOR), Ring, A.8 (AUTHOR), Yap, C.9 (AUTHOR), Rekowski, J.10 (AUTHOR), Dickinson, P.11 (AUTHOR), Ruston, L.12 (AUTHOR), Mcguinness, B.13 (AUTHOR), Cowley, P.13 (AUTHOR), Campbell, G.14 (AUTHOR), Wise, A.15 (AUTHOR), Thomson, C.13 (AUTHOR), Landers, D.16 (AUTHOR), Yap, T.A.17 (AUTHOR) |
| Source: | Annals of Oncology. 2025 Supplement 2, Vol. 36, pS653-S653. 1p. |
| Database: | Academic Search Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: asn DbLabel: Academic Search Ultimate An: 189419381 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=189419381 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.annonc.2025.08.1569 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: S653 Titles: – TitleFull: 1000TiP Novel next generation PARP1-selective and CNS penetrant inhibitor DSB2455: A phase Ia/Ib open label, multi-centre dose escalation study with expansion cohorts to assess the safety, tolerability, and activity as monotherapy in participants with advanced malignancies Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yarza, R. – PersonEntity: Name: NameFull: Garralda, E. – PersonEntity: Name: NameFull: Sánchez Perez, V. – PersonEntity: Name: NameFull: De Velasco Oria, G.A. – PersonEntity: Name: NameFull: Lorusso, P.M. – PersonEntity: Name: NameFull: Rodríguez, R.M. – PersonEntity: Name: NameFull: Kristeleit, R.S. – PersonEntity: Name: NameFull: Ring, A. – PersonEntity: Name: NameFull: Yap, C. – PersonEntity: Name: NameFull: Rekowski, J. – PersonEntity: Name: NameFull: Dickinson, P. – PersonEntity: Name: NameFull: Ruston, L. – PersonEntity: Name: NameFull: Mcguinness, B. – PersonEntity: Name: NameFull: Cowley, P. – PersonEntity: Name: NameFull: Campbell, G. – PersonEntity: Name: NameFull: Wise, A. – PersonEntity: Name: NameFull: Thomson, C. – PersonEntity: Name: NameFull: Landers, D. – PersonEntity: Name: NameFull: Yap, T.A. IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 09 Text: 2025 Supplement 2 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 09237534 Numbering: – Type: volume Value: 36 Titles: – TitleFull: Annals of Oncology Type: main |
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