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Engineered crRNA Drives RPA‐T7‐CRISPR/Cas14a Cascade for Ultrasensitive Detection of ctDNA PIK3CA H1047R.

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Title: Engineered crRNA Drives RPA‐T7‐CRISPR/Cas14a Cascade for Ultrasensitive Detection of ctDNA PIK3CA H1047R.
Authors: Yu, Yuanyuan1 (AUTHOR), Jin, Mengru1 (AUTHOR), Yuan, Weiguang2 (AUTHOR), Gong, Yajie1 (AUTHOR), Li, Siwei1 (AUTHOR), Qin, Xuquan1 (AUTHOR), Hou, Jianxun1 (AUTHOR), Liu, Jialin1 (AUTHOR), Liu, Siyu1 (AUTHOR), Li, Hui1 (AUTHOR), Chu, Yijun1 (AUTHOR), Wang, Yingjie1 (AUTHOR), Zhang, Youxue1 (AUTHOR), Fang, Fang1 (AUTHOR), Hao, Wenhui1 (AUTHOR), Gu, Yuling3 (AUTHOR), Fan, Qinchen1 (AUTHOR), Lin, Jing2 (AUTHOR) linjing@hrbmu.edu.cn, Pang, Da1 (AUTHOR) pangda@ems.hrbmu.edu.cn, Zhang, Xianyu1 (AUTHOR) zhangxianyu@ems.hrbmu.edu.cn
Source: Advanced Science. 11/27/2025, Vol. 12 Issue 44, p1-17. 17p.
Database: Academic Search Ultimate
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ISSN:21983844
DOI:10.1002/advs.202507126