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Transcriptomic profiling reveals crizotinib-induced hepatotoxicity through ROS-mediated activation of the JNK/NLRP3 pathway.

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Title: Transcriptomic profiling reveals crizotinib-induced hepatotoxicity through ROS-mediated activation of the JNK/NLRP3 pathway.
Authors: Li, Min1,2 (AUTHOR), Yue, Zhouli2,3 (AUTHOR), Wang, Menglin2,3 (AUTHOR), Wang, Yan1 (AUTHOR), Xiao, Peng1 (AUTHOR), Yuan, Wei1 (AUTHOR), Shen, Jiduo2,3 (AUTHOR) Shenjiduo@hactcm.edu.cn, Li, Yucheng2,4 (AUTHOR) Liyucheng@hactcm.edu.cn
Source: Toxicology Mechanisms & Methods. Nov2025, Vol. 35 Issue 9, p1314-1323. 10p.
Database: Academic Search Ultimate
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ISSN:15376516
DOI:10.1080/15376516.2025.2536058