Rational design, synthesis, and molecular modelling insights of dual DNA binders/DHFR inhibitors bearing arylidene-hydrazinyl-1,3-thiazole scaffold with apoptotic and anti-migratory potential in breast MCF-7 cancer cells.
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| Title: | Rational design, synthesis, and molecular modelling insights of dual DNA binders/DHFR inhibitors bearing arylidene-hydrazinyl-1,3-thiazole scaffold with apoptotic and anti-migratory potential in breast MCF-7 cancer cells. |
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| Authors: | El-Wakil, Marwa H.1 (AUTHOR) marwa.elwakil@alexu.edu.eg, Ghazala, Rasha A.2 (AUTHOR), El-Dershaby, Hadeel A.1 (AUTHOR), Drozdowska, Danuta3 (AUTHOR), Wróbel-Tałałaj, Agnieszka3 (AUTHOR), Parzych, Cezary4 (AUTHOR), Ratkiewicz, Artur4 (AUTHOR), Kolesińska, Beata5 (AUTHOR), Abd El-Razik, Heba A.1 (AUTHOR), Soliman, Farid S. G.1 (AUTHOR) |
| Source: | Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2025, Vol. 40 Issue 1, p1-21. 21p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 14756366 |
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| DOI: | 10.1080/14756366.2025.2468353 |
