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IFN-γ-driven skewing towards Th1 over Th17 differentiation underlies CRS and neutropenia in CAR-T therapy.

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Bibliographic Details
Title: IFN-γ-driven skewing towards Th1 over Th17 differentiation underlies CRS and neutropenia in CAR-T therapy.
Authors: Goala, Payal1,2, Yongliang Zhang3, Beatty, Nolan1,2, Pavy, Allan4, McSain, Shannon1, Sailer, Cooper1, Tariq, Muhammad Junaid4,5, Hamid, Showkat4,6, Gomez, Eduardo Cortes7, Jianmin Wang7, Massillon, Duna1, Ilecki, Maxwell4, Boucher, Justin C.8, Savid-Frontera, Constanza8, Sae Bom Lee2,8, Kotani, Hiroshi9, Stone, Meredith L.4, Jain, Michael D.6, Davila, Marco L.1,4 Marco.Davila@RoswellPark.org
Source: Journal of Clinical Investigation. 1/2/2026, Vol. 136 Issue 1, p1-17. 17p.
Database: Academic Search Ultimate
Description
ISSN:00219738
DOI:10.1172/JCI194631