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The 3C-like serine protease activity of porcine astrovirus nsP1a/3 mediates mitochondrial apoptosis and MAVS cleavage to facilitate viral replication and antagonize type I interferon response.

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Title: The 3C-like serine protease activity of porcine astrovirus nsP1a/3 mediates mitochondrial apoptosis and MAVS cleavage to facilitate viral replication and antagonize type I interferon response.
Authors: Du, YiYang1,2,3 (AUTHOR), Lv, Yueqing1,2,3 (AUTHOR), Feng, Xiaoying1,2,3 (AUTHOR), Luo, Yuhang1,2,3 (AUTHOR), Wei, Xiaofang1,2,3 (AUTHOR), Shao, Sixiao1,2,3 (AUTHOR), Zhou, Yeli1,2,3 (AUTHOR), Ouyang, Kang1,2,3 (AUTHOR), Yin, Yeshi1,2,3 (AUTHOR), Chen, Ying1,2,3 (AUTHOR), Wei, Zuzhang1,2,3 (AUTHOR), Huang, Weijian1,2,3 (AUTHOR), Qin, Yifeng1,2,3 (AUTHOR) qinyf@gxu.edu.cn
Source: PLoS Pathogens. 2/17/2026, Vol. 22 Issue 2, p1-31. 31p.
Database: Academic Search Ultimate
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  Data: <searchLink fieldCode="JN" term="%22PLoS+Pathogens%22">PLoS Pathogens</searchLink>. 2/17/2026, Vol. 22 Issue 2, p1-31. 31p.
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        Value: 10.1371/journal.ppat.1013987
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              Text: 2/17/2026
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