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Oncogenic PI3Kα variants reveal graded conformational spectrum with mutation-specific cryptic pockets.

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Bibliographic Details
Title: Oncogenic PI3Kα variants reveal graded conformational spectrum with mutation-specific cryptic pockets.
Authors: Jang, Hyunbum1,2 (AUTHOR), Yavuz, Bengi Ruken2 (AUTHOR), Zhang, Mingzhen1 (AUTHOR), Liu, Yonglan2 (AUTHOR), Nussinov, Ruth1,2,3 (AUTHOR) NussinoR@mail.nih.gov
Source: Communications Chemistry. 1/21/2026, Vol. 9 Issue 1, p1-17. 17p.
Database: Academic Search Ultimate
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Description
ISSN:23993669
DOI:10.1038/s42004-026-01906-x