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Oncogenic PI3Kα variants reveal graded conformational spectrum with mutation-specific cryptic pockets.

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Title: Oncogenic PI3Kα variants reveal graded conformational spectrum with mutation-specific cryptic pockets.
Authors: Jang, Hyunbum1,2 (AUTHOR), Yavuz, Bengi Ruken2 (AUTHOR), Zhang, Mingzhen1 (AUTHOR), Liu, Yonglan2 (AUTHOR), Nussinov, Ruth1,2,3 (AUTHOR) NussinoR@mail.nih.gov
Source: Communications Chemistry. 1/21/2026, Vol. 9 Issue 1, p1-17. 17p.
Database: Academic Search Ultimate
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  Data: Oncogenic PI3Kα variants reveal graded conformational spectrum with mutation-specific cryptic pockets.
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  Data: <searchLink fieldCode="AR" term="%22Jang%2C+Hyunbum%22">Jang, Hyunbum</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yavuz%2C+Bengi+Ruken%22">Yavuz, Bengi Ruken</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Mingzhen%22">Zhang, Mingzhen</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Yonglan%22">Liu, Yonglan</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nussinov%2C+Ruth%22">Nussinov, Ruth</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<i> NussinoR@mail.nih.gov</i>
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  Data: <searchLink fieldCode="JN" term="%22Communications+Chemistry%22">Communications Chemistry</searchLink>. 1/21/2026, Vol. 9 Issue 1, p1-17. 17p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=191808711
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        Value: 10.1038/s42004-026-01906-x
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      – Code: eng
        Text: English
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              Text: 1/21/2026
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              Y: 2026
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