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Sustained Drug–Drug Interaction Between Cyclosporine and Apalutamide in a Patient With Metastatic Hormone‐Sensitive Prostate Cancer: A Case Report and Evaluation of CYP3A4 Induction via Pregnane X Receptor Activation by Apalutamide.

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Title: Sustained Drug–Drug Interaction Between Cyclosporine and Apalutamide in a Patient With Metastatic Hormone‐Sensitive Prostate Cancer: A Case Report and Evaluation of CYP3A4 Induction via Pregnane X Receptor Activation by Apalutamide.
Authors: Mimura, Yoshihisa1 (AUTHOR), Sanda, Takaomi2 (AUTHOR), Unno, Rei3 (AUTHOR), Furukawa, Yuki2 (AUTHOR), Shizu, Ryota4 (AUTHOR), Motokatsu, Kotona4 (AUTHOR), Tashiro, Yuusuke1 (AUTHOR), Tasaki, Yoshihiko1 (AUTHOR), Sugiyama, Yosuke1 (AUTHOR), Yasujima, Tomoya5 (AUTHOR), Naiki, Taku3 (AUTHOR), Horita, Yasuhiro1 (AUTHOR), Hotta, Yuji1 (AUTHOR), Yuasa, Hiroaki5 (AUTHOR), Yoshinari, Kouichi4 (AUTHOR), Yasui, Takahiro3 (AUTHOR), Iida, Shinsuke2 (AUTHOR), Furukawa-Hibi, Yoko1 (AUTHOR) yokoh@med.nagoya-cu.ac.jp, Mayordomo, Jose I. (AUTHOR) josemayordomo@hotmail.com
Source: Case Reports in Oncological Medicine. 2/24/2026, Vol. 2026, p1-5. 5p.
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  Data: <searchLink fieldCode="JN" term="%22Case+Reports+in+Oncological+Medicine%22">Case Reports in Oncological Medicine</searchLink>. 2/24/2026, Vol. 2026, p1-5. 5p.
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