An intrinsic loop-mediated structural stability modulating inhibitor potency in the SADS-CoV and SARS-CoV-2 main proteases. - Zeng, Rui; Cui, Shizhan; Xia, Xiaoyan; Huang, Chong; Sun, Jingxuan; Deng, Xinyue; Gui, Qiaoling; Fan, Huahao; Liu, Xiaojuan; Yu, Yang; Yang, Shengyong; Lei, Jian (PLoS Pathogens, 2026)