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Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals.

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Title: Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals.
Authors: Xiong, Xiran1 (AUTHOR), Song, Jun1,2 (AUTHOR), Li, Shihan1 (AUTHOR), Jin, Lu1,2 (AUTHOR), He, Qi1 (AUTHOR), Zhang, Baohui1,2 (AUTHOR), Cao, Yan1,2 (AUTHOR), Yi, Shanyong3 (AUTHOR), Yang, Yanfang1,2 (AUTHOR), Li, Xiang4 (AUTHOR) li.xiang@whu.edu.cn, Li, Juan1,2 (AUTHOR) 2891@hbucm.edu.cn, Huang, Wei1,2 (AUTHOR) 2024wei@hbucm.edu.cn
Source: Advanced Science. 3/3/2026, Vol. 13 Issue 13, p1-15. 15p.
Database: Academic Search Ultimate
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ISSN:21983844
DOI:10.1002/advs.202517794