Study protocol for a multiarm, randomized controlled trial to determine the effectiveness of community-based frailty rehabilitation to improve physical function in older adults: The OPTIMAL Fitness Trial.

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Title: Study protocol for a multiarm, randomized controlled trial to determine the effectiveness of community-based frailty rehabilitation to improve physical function in older adults: The OPTIMAL Fitness Trial.
Authors: Papaioannou, Alexandra1,2,3 (AUTHOR) papaioannou@hhsc.ca, Kennedy, Courtney1,3 (AUTHOR), Lee, Justin1,3 (AUTHOR), Hewston, Patricia1,3,4 (AUTHOR), McArthur, Caitlin3,5 (AUTHOR), Maharaj, Shyam6 (AUTHOR), Adachi, Jonathan1,3 (AUTHOR), Boulos, Pauline1 (AUTHOR), Bobba, Raja1 (AUTHOR), Rabinovich, Alexander7 (AUTHOR), McKenna, Brian8 (AUTHOR), Palubiski, Lisa8 (AUTHOR), Mangin, Dee9 (AUTHOR), Thabane, Lehana2,3,10,11 (AUTHOR), Marr, Sharon1,3 (AUTHOR), Kaasalainen, Sharon12 (AUTHOR), Tarride, Jean-Éric2,13,14 (AUTHOR), Theou, Olga5,15 (AUTHOR), Armstrong, David1 (AUTHOR), Negm, Ahmed3,16 (AUTHOR)
Source: PLoS ONE. 3/12/2026, Vol. 21 Issue 3, p1-23. 23p.
Database: Academic Search Ultimate
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  Data: <searchLink fieldCode="JN" term="%22PLoS+ONE%22">PLoS ONE</searchLink>. 3/12/2026, Vol. 21 Issue 3, p1-23. 23p.
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