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SAMHD1 depletion restricts SARS-CoV-2 infection by suppressing HNF1-dependent ACE2 expression in lung epithelial cells.

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Title: SAMHD1 depletion restricts SARS-CoV-2 infection by suppressing HNF1-dependent ACE2 expression in lung epithelial cells.
Authors: Cheung, Pak-Hin Hinson1 (AUTHOR) pakhinhinson-cheung@uiowa.edu, Chan, Pearl1 (AUTHOR), Yang, Hua1 (AUTHOR), Ambrus, Krisztina2 (AUTHOR), Honne, Shravya2 (AUTHOR), Kim, Baek2 (AUTHOR), Perlman, Stanley1 (AUTHOR), Wu, Li1 (AUTHOR) li-wu@uiowa.edu
Source: PLoS Pathogens. 3/19/2026, Vol. 22 Issue 3, p1-33. 33p.
Database: Academic Search Ultimate
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  Data: SAMHD1 depletion restricts SARS-CoV-2 infection by suppressing HNF1-dependent ACE2 expression in lung epithelial cells.
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  Data: <searchLink fieldCode="AR" term="%22Cheung%2C+Pak-Hin+Hinson%22">Cheung, Pak-Hin Hinson</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> pakhinhinson-cheung@uiowa.edu</i><br /><searchLink fieldCode="AR" term="%22Chan%2C+Pearl%22">Chan, Pearl</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Hua%22">Yang, Hua</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ambrus%2C+Krisztina%22">Ambrus, Krisztina</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Honne%2C+Shravya%22">Honne, Shravya</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Baek%22">Kim, Baek</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Perlman%2C+Stanley%22">Perlman, Stanley</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wu%2C+Li%22">Wu, Li</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> li-wu@uiowa.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22PLoS+Pathogens%22">PLoS Pathogens</searchLink>. 3/19/2026, Vol. 22 Issue 3, p1-33. 33p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=192373053
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        Value: 10.1371/journal.ppat.1013659
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        Text: English
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      – TitleFull: SAMHD1 depletion restricts SARS-CoV-2 infection by suppressing HNF1-dependent ACE2 expression in lung epithelial cells.
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              Text: 3/19/2026
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