Lyophilized monoclonal antibody (mAb) encoded mRNA—lipid nanoparticles (LNPs) lead to stable in vivo expression of mAb after room temperature storage.
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| Title: | Lyophilized monoclonal antibody (mAb) encoded mRNA—lipid nanoparticles (LNPs) lead to stable in vivo expression of mAb after room temperature storage. |
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| Authors: | Wang, Zimeng1 (AUTHOR), Cheng, Bei1 (AUTHOR), Tkaczyk, Christine2 (AUTHOR), Newton, Michael3 (AUTHOR), Cui, Shuolin1 (AUTHOR), Andreiuk, Bohdan1 (AUTHOR), Saha, Sanjib1 (AUTHOR), Khan, Sabrina1 (AUTHOR), Chen, Charles1 (AUTHOR), Yang, Bin4 (AUTHOR), Gamson, Adam2 (AUTHOR), Siddiqui, Sarah2 (AUTHOR), Thom, George5 (AUTHOR), DiGiandomenico, Antonio2 (AUTHOR), Zhou, Liping1 (AUTHOR) liping.zhou1@astrazeneca.com |
| Source: | AAPS Open. 3/23/2026, Vol. 12 Issue 1, p1-13. 13p. |
| Database: | Academic Search Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: asn DbLabel: Academic Search Ultimate An: 192430858 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Lyophilized monoclonal antibody (mAb) encoded mRNA—lipid nanoparticles (LNPs) lead to stable in vivo expression of mAb after room temperature storage. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Wang%2C+Zimeng%22">Wang, Zimeng</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cheng%2C+Bei%22">Cheng, Bei</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tkaczyk%2C+Christine%22">Tkaczyk, Christine</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Newton%2C+Michael%22">Newton, Michael</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cui%2C+Shuolin%22">Cui, Shuolin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Andreiuk%2C+Bohdan%22">Andreiuk, Bohdan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Saha%2C+Sanjib%22">Saha, Sanjib</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Khan%2C+Sabrina%22">Khan, Sabrina</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Charles%22">Chen, Charles</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Bin%22">Yang, Bin</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gamson%2C+Adam%22">Gamson, Adam</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Siddiqui%2C+Sarah%22">Siddiqui, Sarah</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Thom%2C+George%22">Thom, George</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22DiGiandomenico%2C+Antonio%22">DiGiandomenico, Antonio</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhou%2C+Liping%22">Zhou, Liping</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> liping.zhou1@astrazeneca.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22AAPS+Open%22">AAPS Open</searchLink>. 3/23/2026, Vol. 12 Issue 1, p1-13. 13p. |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=192430858 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s41120-026-00147-5 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 1 Titles: – TitleFull: Lyophilized monoclonal antibody (mAb) encoded mRNA—lipid nanoparticles (LNPs) lead to stable in vivo expression of mAb after room temperature storage. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang, Zimeng – PersonEntity: Name: NameFull: Cheng, Bei – PersonEntity: Name: NameFull: Tkaczyk, Christine – PersonEntity: Name: NameFull: Newton, Michael – PersonEntity: Name: NameFull: Cui, Shuolin – PersonEntity: Name: NameFull: Andreiuk, Bohdan – PersonEntity: Name: NameFull: Saha, Sanjib – PersonEntity: Name: NameFull: Khan, Sabrina – PersonEntity: Name: NameFull: Chen, Charles – PersonEntity: Name: NameFull: Yang, Bin – PersonEntity: Name: NameFull: Gamson, Adam – PersonEntity: Name: NameFull: Siddiqui, Sarah – PersonEntity: Name: NameFull: Thom, George – PersonEntity: Name: NameFull: DiGiandomenico, Antonio – PersonEntity: Name: NameFull: Zhou, Liping IsPartOfRelationships: – BibEntity: Dates: – D: 23 M: 03 Text: 3/23/2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 23649534 Numbering: – Type: volume Value: 12 – Type: issue Value: 1 Titles: – TitleFull: AAPS Open Type: main |
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