AI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal embecovirus antigen design.

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Title: AI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal embecovirus antigen design.
Authors: Melchers, Jelle M.1,2 (AUTHOR), Juraszek, Jarek2 (AUTHOR), Hulswit, Ruben J.G.1 (AUTHOR), van Overveld, Daan2 (AUTHOR), Le, Lam2 (AUTHOR), van Kuppeveld, Frank J.M.1 (AUTHOR), Hurdiss, Daniel L.1 (AUTHOR), Bosch, Berend-Jan1 (AUTHOR), Langedijk, Johannes P.M.2,3 (AUTHOR), Bakkers, Mark J.G.2,3 (AUTHOR) mbakkers@forge-bio.com
Source: PLoS Pathogens. 3/23/2026, Vol. 22 Issue 3, p1-22. 22p.
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  Data: AI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal embecovirus antigen design.
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  Data: <searchLink fieldCode="AR" term="%22Melchers%2C+Jelle+M%2E%22">Melchers, Jelle M.</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Juraszek%2C+Jarek%22">Juraszek, Jarek</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hulswit%2C+Ruben+J%2EG%2E%22">Hulswit, Ruben J.G.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22van+Overveld%2C+Daan%22">van Overveld, Daan</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Le%2C+Lam%22">Le, Lam</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22van+Kuppeveld%2C+Frank+J%2EM%2E%22">van Kuppeveld, Frank J.M.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hurdiss%2C+Daniel+L%2E%22">Hurdiss, Daniel L.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bosch%2C+Berend-Jan%22">Bosch, Berend-Jan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Langedijk%2C+Johannes+P%2EM%2E%22">Langedijk, Johannes P.M.</searchLink><relatesTo>2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bakkers%2C+Mark+J%2EG%2E%22">Bakkers, Mark J.G.</searchLink><relatesTo>2,3</relatesTo> (AUTHOR)<i> mbakkers@forge-bio.com</i>
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  Data: <searchLink fieldCode="JN" term="%22PLoS+Pathogens%22">PLoS Pathogens</searchLink>. 3/23/2026, Vol. 22 Issue 3, p1-22. 22p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=192462031
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              Text: 3/23/2026
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