A quantitative cell-based reporter links TDP-43 aggregation and dysfunction to define pathogenic mechanisms. - Mamede, Lohany Dias; Hu, Miwei; Vaquer-Alicea, Jaime; Titus, Amanda R.; Passos, Patricia M.; Lantelme, Erica; French, Rachel L.; Kirschner, Paige A.; Diamond, Marc I.; Miller, Timothy M.; Ayala, Yuna M. (PLoS Biology, 2026)