Double-CRISPR Knockout Simulation (DKOsim): A Monte-Carlo randomization system to model cell growth behavior and infer the optimal library design for growth-based double knockout screens.

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Title: Double-CRISPR Knockout Simulation (DKOsim): A Monte-Carlo randomization system to model cell growth behavior and infer the optimal library design for growth-based double knockout screens.
Authors: Gu, Yue1,2 (AUTHOR), Hart, Traver3 (AUTHOR), Leon-Novelo, Luis2 (AUTHOR) Jshen8@mdanderson.org, Shen, John Paul1 (AUTHOR) Luis.G.LeonNovelo@uth.tmc.edu
Source: PLoS Computational Biology. 4/17/2026, Vol. 22 Issue 4, p1-27. 27p.
Database: Academic Search Ultimate
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  Data: Double-CRISPR Knockout Simulation (DKOsim): A Monte-Carlo randomization system to model cell growth behavior and infer the optimal library design for growth-based double knockout screens.
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  Data: <searchLink fieldCode="AR" term="%22Gu%2C+Yue%22">Gu, Yue</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hart%2C+Traver%22">Hart, Traver</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Leon-Novelo%2C+Luis%22">Leon-Novelo, Luis</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> Jshen8@mdanderson.org</i><br /><searchLink fieldCode="AR" term="%22Shen%2C+John+Paul%22">Shen, John Paul</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> Luis.G.LeonNovelo@uth.tmc.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22PLoS+Computational+Biology%22">PLoS Computational Biology</searchLink>. 4/17/2026, Vol. 22 Issue 4, p1-27. 27p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=193088193
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        Value: 10.1371/journal.pcbi.1013510
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        Text: English
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      – TitleFull: Double-CRISPR Knockout Simulation (DKOsim): A Monte-Carlo randomization system to model cell growth behavior and infer the optimal library design for growth-based double knockout screens.
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            NameFull: Hart, Traver
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              Text: 4/17/2026
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              Y: 2026
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