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Rapid directed evolution guided by protein language models and epistatic interactions.

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Title: Rapid directed evolution guided by protein language models and epistatic interactions.
Authors: Tran, Vincent Q.1,2 (AUTHOR), Nemeth, Matthew1 (AUTHOR), Bartie, Liam J.1 (AUTHOR), Chandrasekaran, Sita S.1,3,4 (AUTHOR), Fanton, Alison1,3,4 (AUTHOR), Moon, Hyungseok C.1 (AUTHOR), Hie, Brian L.1,5,6 (AUTHOR), Konermann, Silvana1,7 (AUTHOR), Hsu, Patrick D.1,3,8 (AUTHOR) patrick@arcinstitute.org
Source: Science. 5/7/2026, Vol. 392 Issue 6798, p1-13. 13p.
Database: Academic Search Ultimate
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  Data: Rapid directed evolution guided by protein language models and epistatic interactions.
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  Data: <searchLink fieldCode="AR" term="%22Tran%2C+Vincent+Q%2E%22">Tran, Vincent Q.</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nemeth%2C+Matthew%22">Nemeth, Matthew</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bartie%2C+Liam+J%2E%22">Bartie, Liam J.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chandrasekaran%2C+Sita+S%2E%22">Chandrasekaran, Sita S.</searchLink><relatesTo>1,3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fanton%2C+Alison%22">Fanton, Alison</searchLink><relatesTo>1,3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Moon%2C+Hyungseok+C%2E%22">Moon, Hyungseok C.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hie%2C+Brian+L%2E%22">Hie, Brian L.</searchLink><relatesTo>1,5,6</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Konermann%2C+Silvana%22">Konermann, Silvana</searchLink><relatesTo>1,7</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hsu%2C+Patrick+D%2E%22">Hsu, Patrick D.</searchLink><relatesTo>1,3,8</relatesTo> (AUTHOR)<i> patrick@arcinstitute.org</i>
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  Data: <searchLink fieldCode="JN" term="%22Science%22">Science</searchLink>. 5/7/2026, Vol. 392 Issue 6798, p1-13. 13p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=193588359
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              Text: 5/7/2026
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