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LP.8.1-directed COVID-19 mRNA vaccines durably boost neutralizing antibodies and mitigate ancestral immune imprinting.

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Title: LP.8.1-directed COVID-19 mRNA vaccines durably boost neutralizing antibodies and mitigate ancestral immune imprinting.
Authors: Mellis, Ian A.1,2 (AUTHOR) im2613@cumc.columbia.edu, Wu, Madeline1 (AUTHOR), Hong, Hsiang1,3 (AUTHOR), Bowen, Anthony1,4 (AUTHOR), Daniel, Kristin1,2 (AUTHOR), Gherasim, Carmen5 (AUTHOR), Pierce, Virginia M.5 (AUTHOR), Yin, Michael T.1,4 (AUTHOR), Gordon, Aubree6 (AUTHOR) gordonal@umich.edu, Guo, Yicheng1 (AUTHOR) yg2521@cumc.columbia.edu, Ho, David D.1,4,7,8 (AUTHOR) dh2994@cumc.columbia.edu
Source: PLoS Pathogens. 5/11/2026, Vol. 22 Issue 5, p1-9. 9p.
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  Data: LP.8.1-directed COVID-19 mRNA vaccines durably boost neutralizing antibodies and mitigate ancestral immune imprinting.
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