N-Substituted-2-(9H-Xanthen-9-yl)acetamide Derivatives Induce In Vitro Colon Cancer Cell Death via TASK-1 Inhibition: Lead Compounds for Further Optimization as TASK-1-Targeted Therapeutics in Colorectal Cancer.

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Title: N-Substituted-2-(9H-Xanthen-9-yl)acetamide Derivatives Induce In Vitro Colon Cancer Cell Death via TASK-1 Inhibition: Lead Compounds for Further Optimization as TASK-1-Targeted Therapeutics in Colorectal Cancer.
Authors: Al Khzem, Abdulaziz H.1 (AUTHOR), El Rayes, S. M.2 (AUTHOR), Ali, Ibrahim A. I.2,3 (AUTHOR), Fathalla, Walid3,4 (AUTHOR), Alturki, Mansour S.1,5 (AUTHOR), Tawfeeq, Nada1,6 (AUTHOR), Tayeb, Saeed M.4,7 (AUTHOR), Alfattani, Abdulelah A.1,4 (AUTHOR), Wali, Saad M.2,5 (AUTHOR), Khan, Firdos A.3,6 (AUTHOR), Alqarni, Abdulmalik M.1,4 (AUTHOR), Pottoo, Faheem H.5,7 (AUTHOR), Hussein, Dania6,7 (AUTHOR), Gomaa, Mohamed S.1,7 (AUTHOR)
Source: International Journal of Molecular Sciences. May2026, Vol. 27 Issue 9, p4069. 34p.
Database: Academic Search Ultimate
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ISSN:16616596
DOI:10.3390/ijms27094069